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TLC Pharmaceutical Standards

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SOFOSBUVIR

S-055026

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Catalogue Number:	S-055026
Compound Name:	Sofosbuvir Impurity 49 (GS-566500)-13C-d3 Ditriethylamine Salt
Synonyms:	((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)-L-alanine, triethylamine (1:2)
CAS#:
Alternate CAS#:	1256490-46-6 (free acid)
Molecular Formula:	C₁₂¹³CH₁₆D₃FN₃O₉P. 2 Et₃N
Molecular Weight:	415.29 2*101.19

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C24H22FN3O6

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C24H20N2O7

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Sofosbuvir Impurity 11

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Sofosbuvir Nucleoside Derivative (GS-331007)

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M.W. 260.22

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M.W. 372.35

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Sofosbuvir Impurity 31

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C10H16FN2O14P3

M.W. 500.16

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Sofosbuvir Impurity 32

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M.W. C20H17FO6

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M.W. C20H17ClO6

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Sofosbuvir Impurity 31-13C-d3

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Sofosbuvir Nucleoside Derivative (GS-331007)

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M.W. 287.25 99.18

S-055050

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 44

C₂₂H₂₉FN₃O₉P

M.W. 529.46

S-055051

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Sofosbuvir Impurity 45

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C18H17F5NO5P

M.W. 453.31

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Sofosbuvir Impurity 46

C₂₂H₂₉FN₃O₉P

M.W. 529.46

S-055053

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Sofosbuvir Impurity 47-13C-d3

C₂₇¹³CH₃₀D₃FN₃O₉P

M.W. 609.57

S-055054

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 48

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M.W. 529.46

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Sofosbuvir Impurity 51

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Sofosbuvir Impurity 52

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C₂₉H₃₃FN₃O₁₀P

M.W. 633.57

S-055060

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Sofosbuvir Impurity 53

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M.W. 501.40

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Sofosbuvir Impurity 54

C17H17FN2O6

M.W. 364.33

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Sofosbuvir Impurity 55

C17H17FN2O6

M.W. 364.33

S-055063

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 56

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C₃₁H₂₆FN₃O₇

M.W. 571.56

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Sofosbuvir Impurity 57

C24H21ClN2O7

M.W. 484.89

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Sofosbuvir Impurity 58

C31H26ClN3O7

M.W. 588.01

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Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 59

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C₃₁H₂₆FN₃O₇

M.W. 571.56

S-055067

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 60

C31H26FN3O7

M.W. 571.56

S-055068

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 61

C31H26FN3O7

M.W. 571.56

S-055069

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 62

C31H27N3O8

M.W. 569.57

S-055070

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 63

CAS No. 1334513-02-8

C₁₈H₁₇F₅NO₅P

M.W. 453.30

S-055071

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 64

CAS No. 1714114-25-6

C₁₈H₁₇F₅NO₅P

M.W. 453.30

S-055072

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 65

CAS No. 1627824-09-2

C₁₈H₁₇F₅NO₅P

M.W. 453.30

S-055073

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 66

C12H17ClNO4P

M.W. 305.69

S-055074

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 67

C16H13F5NO5P

M.W. 425.25

S-055075

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 68

C31H26FN3O7

M.W. 571.56

S-055076

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 69

C31H26FN3O7

M.W. 571.56

S-055077

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 70

C12H15FN2O6

M.W. 302.26

S-055078

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 71

C12H15FN2O6

M.W. 302.26

S-055079

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 72

C14H17FN2O7

M.W. 344.30

S-055080

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 73

C24H31FN3O10P

M.W. 571.50

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Sofosbuvir Impurity 74

C24H31FN3O10P

M.W. 571.50

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Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 75

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M.W. 571.50

S-055083

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 76

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C21H27FN3O9P

M.W. 515.43

S-055084

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 77

CAS No. 1337482-17-3

C34H45FN4O13P2

M.W. 798.69

S-055085

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir-d6

CAS No. 1868135-06-1

C22H23D6FN3O9P

M.W. 535.49

S-055086

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 78

C20H17FO6

M.W. 372.35

S-055087

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 79

C20H17FO6

M.W. 372.35

S-055088

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 80

C₂₂H₂₉FN₃O₉P

M.W. 529.46

S-055089

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 81

C₂₀H₁₉FO₆

M.W. 374.36

S-055090

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 82

C₃₁H₂₆FN₃O₇

M.W. 571.56

S-055091

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 83

C₃₁H₂₆FN₃O₇

M.W. 571.56

S-055092

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 84

CAS No. 1884385-12-9

C₂₀H₁₉FO₆

M.W. 374.36

S-055093

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 85

CAS No. 1621160-31-3

C₂₀H₁₈ClFO₅

M.W. 392.81

S-055094

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 86

CAS No. 22224-41-5

C₂₆H₂₂O₈

M.W. 462.45

S-055095

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 87

CAS No. 157037-56-4

C₂₆H₂₀O₈

M.W. 460.44

S-055096

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 88

CAS No. 30361-19-4

C₃₄H₂₈O₉

M.W. 580.59

S-055097

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 89

C₃₈H₃₁N₃O₉

M.W. 673.68

S-055098

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 90

C₁₃H₁₉FN₃O₉P

M.W. 411.28

S-055099

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 91

CAS No. 817204-35-6

C₁₇H₁₉N₃O₆

M.W. 361.35

S-055100

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 92

CAS No. 863329-64-0

C₃₁H₂₇N₃O₈

M.W. 569.57

S-055101

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 93

C₁₃H₁₃FO₅

M.W. 268.24

S-055102

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 94

C₁₃H₁₃FO₅

M.W. 268.24

S-055103

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 95

CAS No. 7392-74-7

C₂₇H₂₂O₈

M.W. 474.46

S-055104

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 96

CAS No. 15186-48-8

C₆H₁₀O₃

M.W. 130.14

S-055105

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 97

CAS No. 1946820-91-2

C₂₀H₁₇FO₆

M.W. 372.34

S-055106

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 98

CAS No. 1033394-94-3

C₂₀H₁₇FO₆

M.W. 372.34

S-055107

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 99

C₂₄H₃₄N₂O₉P₂

M.W. 556.48

S-055108

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 100

C₂₄H₂₂F₅NO₈P₂

M.W. 609.37

S-055109

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 101

C₁₈H₁₇F₅NO₅P

M.W. 453.30

S-055110

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 102

C₁₈H₁₈F₄NO₅P

M.W. 435.31

S-055111

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 103

C₁₈H₁₈F₄NO₅P

M.W. 435.31

S-055112

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 104

C₁₈H₁₈F₄NO₅P

M.W. 435.31

S-055113

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 105

CAS No. 1496552-28-3

C₂₂H₂₉FN₃O₉P

M.W. 529.46

S-055114

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 49 (GS-566500) Ditriethylamine Salt

C₁₃H₁₉FN₃O₉P. 2 Et₃N

M.W. 411.28 2*101.19

S-055115

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 106

C₂₂H₂₈N₃O₉P

M.W. 509.45

S-055116

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 107

CAS No. 879551-04-9

C₆H₉FO₄

M.W. 164.13

S-055117

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 108

CAS No. 729596-46-7

C₂₀H₁₈O₇

M.W. 370.36

S-055118

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 109

CAS No. 1639833-40-1

C₂₀H₁₇FO₆

M.W. 372.35

S-055119

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 110

C₂₀H₁₇FO₆

M.W. 372.35

S-055120

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 111

C₂₄H₂₂FN₃O₆

M.W. 467.45

S-055121

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 112

C₂₄H₂₁FN₂O₇

M.W. 468.44

S-055122

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 113

CAS No. 23643-36-9

C₃₁H₂₆N₂O₉

M.W. 570.55

S-055123

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 114

CAS No. 944476-44-2

C₂₄H₂₂N₂O₈

M.W. 466.45

S-055124

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 115

CAS No. 817204-33-4

C₁₀H₁₄FN₃O₄

M.W. 259.24

S-055125

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 116

C₂₁H₂₂F₅N₂O₆P

M.W. 524.38

S-055126

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 117

CAS No. 1392015-05-2

C₁₇H₁₅F₅NO₅P

M.W. 439.27

S-055127

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 118

C₂₉H₃₃FN₃O₁₀P

M.W. 633.57

S-055128

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 119

CAS No. 1334513-10-8

C₂₂H₃₀FN₄O₈P

M.W. 528.47

S-055129

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 120

CAS No. 1859162-79-0

C₁₉H₂₃FN₃O₉P

M.W. 487.38

S-055130

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 121

CAS No. 863329-65-1

C₂₄H₂₁FN₂O₇

M.W. 468.44

S-055131

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 122

CAS No. 31448-54-1

C₁₀H₁₄N₂O₆

M.W. 258.23

S-055132

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 34 Disodium Salt (GS-606965 Disodium Salt)

C₁₀H₁₂FN₂O₈P. 2 Na

M.W. 384.16 2*22.99

S-055133

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 123

CAS No. 119804-96-5

C₁₀H₁₃N₃O₄

M.W. 239.23

S-055134

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 124

CAS No. 130954-03-9

C₁₇H₁₇N₃O₅

M.W. 343.34

S-055135

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 125

CAS No. 4009-39-6

C₇H₉O₄P

M.W. 188.12

S-055136

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 126

C₃₁H₂₆FN₃O₇

M.W. 571.56

S-055137

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 127

C₃₁H₂₆FN₃O₇

M.W. 571.56

S-055138

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 128

CAS No. 2500766-09-4

C₂₃H₃₂N₃O₁₀P

M.W. 541.49

S-055139

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 129

CAS No. 1689524-82-0

C₂₉H₃₄FN₄O₉P

M.W. 632.58

S-055140

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 130

C₁₈H₂₃NO₈P₂

M.W. 443.33

S-055141

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 131

C₂₄H₂₇NO₈P₂

M.W. 519.43

S-055142

Sofosbuvir Nucleoside Derivative (GS-331007)

Sofosbuvir Impurity 41 Triethylamine Salt

C₁₆H₂₅FN₃O₉P. Et₃N

M.W. 453.36 101.19