TLC Pharmaceutical Standards

TLC Pharmaceutical Standards

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NILOTINIB

N-3126

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Catalogue Number:	N-3126
Compound Name:	Nilotinib Impurity 21
Synonyms:	3-((5-chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
CAS#:	2469039-94-7
Alternate CAS#:
Molecular Formula:	C₂₈H₂₁ClF₃N₇O
Molecular Weight:	563.97

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Nilotinib Impurity 1 HCl

C₁₂H₁₂F₃N₃. HCl

M.W. 255.24 36.46

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Nilotinib Impurity 2

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C₁₁H₁₀F₃N₃

M.W. 241.22

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Nilotinib Impurity 3

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C10H8F3N3

M.W. 227.19

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Nilotinib Impurity 4

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C12H12F3N3

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Nilotinib Impurity 5

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C11H10F3N3

M.W. 241.22

N-3110

Nilotinib

Nilotinib Impurity 6

CAS No. 641571-05-3

C₂₈H₂₂F₃N₇O

M.W. 529.53

N-3111

Nilotinib

Nilotinib EP Impurity E

CAS No. 2119583-26-3

C₂₇H₂₀F₃N₇O

M.W. 515.50

N-3112

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Nilotinib Impurity 8

CAS No. N/A

C29H24F3N7O

M.W. 543.56

N-3113

Nilotinib

Nilotinib EP Impurity H

CAS No. 641571-15-5

C₂₈H₂₂F₃N₇O

M.W. 529.53

N-3114

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Nilotinib Impurity 10

CAS No. N/A

C21H22N4O2

M.W. 362.44

N-3115

Nilotinib

Nilotinib EP Impurity F

CAS No. 2119583-24-1

C₂₉H₂₄F₃N₇O

M.W. 543.55

N-3116

Nilotinib

Nilotinib Impurity 12

CAS No. 641571-12-2

C₁₂H₈F₃N₃

M.W. 251.21

N-3117

Nilotinib

Nilotinib Impurity 13

CAS No. 917391-28-7

C₁₂H₁₀F₃N₃O

M.W. 269.23

N-3118

Nilotinib

Nilotinib Impurity 14

CAS No. 641571-13-3

C12H9F3N2O2

M.W. 270.21

N-3119

Nilotinib

Nilotinib Impurity 15

CAS No. 916975-92-3

C11H8F3N3O2

M.W. 271.20

N-3120

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Nilotinib N-Oxide (Imidazole N-Oxide)

CAS No. 2139382-75-3

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3121

Nilotinib

Nilotinib N-Oxide (Pyrimidine N3-Oxide)

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3122

Nilotinib

Nilotinib Impurity 17

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C₁₇H₁₅N₅O

M.W. 305.34

N-3123

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Nilotinib Impurity 18

C18H16N4O

M.W. 304.35

N-3124

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Nilotinib Impurity 19

C18H18N4O

M.W. 306.37

N-3125

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Nilotinib EP Impurity D

CAS No. 641569-94-0

C₁₇H₁₄N₄O₂

M.W. 306.33

N-3127

Nilotinib

Nilotinib Impurity 22

C₁₁H₁₅N₃O₂. HNO₃

M.W. 221.26 63.01

N-3128

Nilotinib

Nilotinib EP Impurity G

CAS No. 917392-54-2

C₁₈H₁₆N₄O₂

M.W. 320.35

N-3129

Nilotinib

Nilotinib EP Impurity A (Nilotinib USP Related Compound A)

CAS No. 641571-11-1

C₁₁H₁₀F₃N₃

M.W. 241.22

N-3130

Nilotinib

Nilotinib EP Impurity B (Nilotinib USP Related Compound B)

CAS No. 18595-18-1

C₉H₁₁NO₂

M.W. 165.19

N-3131

Nilotinib

Nilotinib EP Impurity C (Nilotinib USP Related Compound C)

CAS No. 2458-12-0

C₈H₉NO₂

M.W. 151.17

N-3132

Nilotinib

Nilotinib Impurity 27

CAS No. 1807606-80-9

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3133

Nilotinib

Nilotinib Impurity 28

CAS No. 1807607-72-2

C₂₈H₂₀F₃N₇O₃

M.W. 559.51

N-3134

Nilotinib

Nilotinib Impurity 29

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3135

Nilotinib

Nilotinib Impurity 30

CAS No. 1157857-29-8

C₁₉H₁₅F₃N₄O₃

M.W. 404.35

N-3136

Nilotinib

Nilotinib Impurity 31

CAS No. 915711-42-1

C₁₉H₁₇F₃N₄O

M.W. 374.37

N-3137

Nilotinib

Nilotinib Impurity 32

C₃₂H₂₆F₃N₇O₆

M.W. 661.60

N-3138

Nilotinib

Nilotinib Impurity 33

C₃₂H₂₅F₃N₇O₅+

M.W. 644.59

N-3139

Nilotinib

Nilotinib N-Oxide (Pyrimidine N1-Oxide)

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3140

Nilotinib

Nilotinib Impurity 23

C₂₉H₂₂F₃N₇O₃

M.W. 573.54

N-3141

Nilotinib

Nilotinib Impurity 34

CAS No. 63156-74-1

C₁₁H₁₀F₃N₃

M.W. 241.22

N-3142

Nilotinib

N-Nitroso Nilotinib

CAS No. 2925306-68-7

C₂₈H₂₁F₃N₈O₂

M.W. 558.53

N-3143

Nilotinib

Nilotinib Di-N-Oxide

C₂₈H₂₂F₃N₇O₃

M.W. 561.53

N-3144

Nilotinib

N-Nitroso Nilotinib EP Impurity D Sodium Salt

C₁₇H₁₂N₅O₃. Na

M.W. 334.32 22.99

N-3145

Nilotinib

N-Nitroso Nilotinib N-Oxide (Pyridine N-Oxide)

C₂₈H₂₁F₃N₈O₃

M.W. 574.52

N-3146

Nilotinib

Nilotinib Impurity 35

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M.W. 334.38

N-3147

Nilotinib

Nilotinib Impurity 36

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M.W. 179.22

N-3148

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Nilotinib Impurity 37 Nitrate

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M.W. 221.26 63.01

N-3149

Nilotinib

N-Nitroso Nilotinib Impurity 37

C₁₁H₁₄N₄O₃

M.W. 250.26

N-3150

Nilotinib

Nilotinib N-Oxide (Imidazole N2-Oxide)

C₂₈H₂₂F₃N₇O₂

M.W. 545.53

N-3151

Nilotinib

N-Nitroso Nilotinib EP Impurity E

C₂₇H₁₉F₃N₈O₂

M.W. 544.50

N-3152

Nilotinib

N-Nitroso Nilotinib EP Impurity G

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M.W. 349.35