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TLC Pharmaceutical Standards

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LINAGLIPTIN

L-4437

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Catalogue Number:	L-4437
Compound Name:	Linagliptin Impurity 43
Synonyms:	tert-Butyl (R)-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate
CAS#:	668273-75-4
Alternate CAS#:
Molecular Formula:	C₃₀H₃₆N₈O₄
Molecular Weight:	572.67

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Linagliptin Dimer Impurity 1 (Mixture of DIastereomers)

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M.W. 986.16

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Linagliptin

Linagliptin Dimer Impurity 2

CAS No. 1418133-47-7

C₅₀H₅₆N₁₆O₄

M.W. 945.11

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Linagliptin

Linagliptin Phthalimide Impurity

C33H32N8O4

M.W. 604.67

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Linagliptin

Linagliptin Dimer Impurity 3 (Mixture of Diastereomers)

C₅₂H₅₈N₁₆O₄

M.W. 971.14

L-448

Linagliptin

Linagliptin Metabolite CD1790

CAS No. 1620278-39-8

C₂₅H₂₇N₇O₃

M.W. 473.54

L-449

Linagliptin

Linagliptin Impurity 35

CAS No. 2138392-83-1

C₂₆H₂₁BrN₈O₂

M.W. 557.41

L-4410

Linagliptin

Linagliptin Impurity 36

C20H18N6O3

M.W. 390.40

L-4411

Linagliptin

Linagliptin Impurity 37

C19H26N4O2

M.W. 342.44

L-4412

Linagliptin

Linagliptin Impurity 38

C36H40N10O4

M.W. 676.78

L-4413

Linagliptin

Linagliptin Impurity 39

C₃₁H₃₂N₁₀O₂

M.W. 576.67

L-4414

Linagliptin

Linagliptin Impurity 40

C₁₅H₂₀N₄

M.W. 256.35

L-4415

Linagliptin

Linagliptin Impurity 41

CAS No. 1638744-06-5

C25H29BrN8O2

M.W. 553.47

L-4416

Linagliptin

Linagliptin-13C-d3

CAS No. 1398044-43-3

C₂₄¹³CH₂₅D₃N₈O₂

M.W. 476.56

L-4417

Linagliptin

Linagliptin Impurity 4

CAS No. N/A

C35H36N10O2

M.W. 628.74

L-4418

Linagliptin

Linagliptin Impurity 5

CAS No. 2253964-85-9

C₂₅H₂₈N₈O₂

M.W. 472.55

L-4419

Linagliptin

Linagliptin Impurity 6 TriHCl

C₅₀H₅₆N₁₆O₄. 3 HCl

M.W. 945.11 3*36.46

L-4420

Linagliptin

Linagliptin Impurity 7

CAS No. 2416949-69-2

C₂₅H₂₉N₇O₄

M.W. 491.55

L-4421

Linagliptin

Linagliptin Impurity 8

C₂₆H₂₈N₈O₃

M.W. 500.56

L-4422

Linagliptin

Linagliptin Impurity 9

C27H33N9O2

M.W. 515.62

L-4423

Linagliptin

(S)-Linagliptin

CAS No. 668270-11-9

C₂₅H₂₈N₈O₂

M.W. 472.55

L-4424

Linagliptin

Linagliptin Impurity I

C23H26N8O4

M.W. 478.51

L-4425

Linagliptin

Linagliptin Impurity 53

C25H26N8O3

M.W. 486.54

L-4426

Linagliptin

Linagliptin Dimer Impurity 4

CAS No. 2463617-49-2

C₅₁H₅₆N₁₆O₄

M.W. 957.12

L-4427

Linagliptin

Linagliptin Dimer Impurity 5

C60H62N18O4

M.W. 1099.28

L-4429

Linagliptin

Linagliptin Impurity 12

C31H38N8O7

M.W. 634.70

L-4430

Linagliptin

Linagliptin Impurity 13

C20H18BrN5O4

M.W. 472.30

L-4431

Linagliptin

Linagliptin Impurity 14

CAS No. 2253964-98-4

C₄₅H₄₄N₁₄O₄

M.W. 844.94

L-4432

Linagliptin

Linagliptin Impurity 15

CAS No. 1803079-49-3

C₂₇H₃₀N₈O₃

M.W. 514.59

L-4433

Linagliptin

Linagliptin Impurity 16

CAS No. 1911621-52-7

C₂₀H₁₈N₆O₂

M.W. 374.40

L-4434

Linagliptin

Linagliptin Impurity 17

CAS No. 2489212-72-6

C51H56N16O4

M.W. 957.12

L-4435

Linagliptin

Linagliptin Impurity 18

CAS No. 1646355-34-1

C₂₂H₂₃N₇O₂

M.W. 417.47

L-4436

Linagliptin

Linagliptin Impurity 42

CAS No. 666816-98-4

C₁₀H₉BrN₄O₂

M.W. 297.11

L-4438

Linagliptin

Linagliptin Impurity 102

C₂₆H₂₈N₈O₃

M.W. 500.56

L-4439

Linagliptin

N-Aminoacyl Linagliptin

C₂₆H₂₉N₉O₃

M.W. 515.58

L-4440

Linagliptin

Linagliptin Impurity 20

C20H28N4O2

M.W. 356.47

L-4441

Linagliptin

Linagliptin Impurity 21

CAS No. 666816-91-7

C20H28N6O4

M.W. 416.48

L-4442

Linagliptin

Linagliptin Impurity 22

CAS No. 2518331-40-1

C₂₄H₃₂N₆O₄

M.W. 468.56

L-4443

Linagliptin

Linagliptin Impurity 23

C26H32N8O4

M.W. 520.60

L-4444

Linagliptin

Linagliptin Impurity 24

C11H24N4

M.W. 212.34

L-4445

Linagliptin

Linagliptin Impurity 25

C25H28N8O2

M.W. 472.55

L-4446

Linagliptin

Linagliptin Impurity 26

C25H28N8O2

M.W. 472.55

L-4447

Linagliptin

Linagliptin Tartaric Acid Impurity

C29H32N8O7

M.W. 604.63

L-4448

Linagliptin

Linagliptin Impurity 27

CAS No. 1446263-38-2

C₂₅H₂₈N₈O₂

M.W. 472.55

L-4449

Linagliptin

Linagliptin Impurity 28

C20H19BrN6O2

M.W. 455.32

L-4450

Linagliptin

Linagliptin Impurity 29

C20H19BrN6O2

M.W. 455.32

L-4451

Linagliptin

Linagliptin Impurity 30

C20H17BrN6O2

M.W. 453.30

L-4452

Linagliptin

Linagliptin Impurity 31

C20H17BrN6O2

M.W. 453.30

L-4428

Linagliptin

Linagliptin-d4

CAS No. 2140263-92-7

C₂₅H₂₄D₄N₈O₂

M.W. 476.58

L-4453

Linagliptin

Linagliptin Impurity 32

CAS No. 853029-57-9

C₂₀H₁₇BrN₆O₂

M.W. 453.30

L-4454

Linagliptin

Linagliptin Impurity 33

CAS No. 2468656-63-3

C₂₁H₂₁N₇O₂

M.W. 403.45

L-4455

Linagliptin

Linagliptin Dimer Impurity 6

CAS No. 1643364-41-3

C₅₄H₆₂N₁₆O₄

M.W. 999.20

L-4456

Linagliptin

Linagliptin Impurity 34

CAS No. 13535-91-6

C₁₀H₁₀N₂O

M.W. 174.20

L-4457

Linagliptin

Linagliptin Impurity 44

CAS No. 109113-72-6

C₁₀H₉ClN₂

M.W. 192.65

L-4458

Linagliptin

Linagliptin Impurity 45

CAS No. 93703-24-3

C₆H₅BrN₄O₂

M.W. 245.04

L-4459

Linagliptin

Linagliptin Impurity 46

C₂₅H₂₈N₈O₃

M.W. 488.55

L-4460

Linagliptin

Linagliptin Impurity 47

CAS No. 2074688-84-7

C₂₂H₂₃N₇O₃

M.W. 433.47

L-4461

Linagliptin

Linagliptin Impurity 48

CAS No. 886588-63-2

C₃₃H₃₀N₈O₄

M.W. 602.66

L-4462

Linagliptin

Linagliptin Impurity 49

CAS No. 2074688-81-4

C₃₃H₃₂N₈O₅

M.W. 620.67

L-4463

Linagliptin

Linagliptin Impurity 50 HCl

C₃₈H₄₂N₁₀O₄. HCl

M.W. 702.82 36.46

L-4464

Linagliptin

Linagliptin Impurity 51

CAS No. 2074688-82-5

C₅₈H₅₈N₁₆O₆

M.W. 1075.21

L-4465

Linagliptin

Linagliptin Impurity 52

C26H30N8O2

M.W. 486.58

L-4466

Linagliptin

Linagliptin Impurity 54

C₁₈H₁₇N₃O

M.W. 291.35

L-4467

Linagliptin

Linagliptin Impurity 55 (Mixture of Z and E Isomers)

C₂₅H₂₆N₈O₃

M.W. 486.54

L-4468

Linagliptin

Linagliptin Impurity 56

C₁₀H₁₀Br₂N₄O₂

M.W. 378.02

L-4469

Linagliptin

Linagliptin Impurity 57

C₁₀H₉BrN₄O₂

M.W. 297.11

L-4470

Linagliptin

Linagliptin Impurity 58

C₁₀H₉BrN₄O₂

M.W. 297.11

L-4471

Linagliptin

Linagliptin Impurity 59

C₁₀H₁₂N₂O₂

M.W. 192.22

L-4472

Linagliptin

Linagliptin Impurity 60

C₂₁H₂₉N₅O₃

M.W. 399.50

L-4473

Linagliptin

Linagliptin Impurity 61

C₃₀H₃₆N₈O₄

M.W. 572.67

L-4474

Linagliptin

Linagliptin Impurity 62

C₃₀H₃₆N₈O₄

M.W. 572.67

L-4475

Linagliptin

Linagliptin Impurity 63

C₂₅H₂₈N₈O₂

M.W. 472.55

L-4476

Linagliptin

Linagliptin Impurity 64

CAS No. 2446799-72-8

C₂₅H₂₈N₈O₂

M.W. 472.55

L-4477

Linagliptin

Linagliptin Impurity 65

CAS No. 1339955-47-3

C₂₂H₂₆N₈O₂

M.W. 434.50

L-4478

Linagliptin

Linagliptin Impurity 66

C₂₅H₂₆N₈O₃

M.W. 486.213

L-4479

Linagliptin

Linagliptin Impurity 67 (2-Aminoacetophenone)

CAS No. 551-93-9

C₈H₉NO

M.W. 135.068

L-4480

Linagliptin

Linagliptin Impurity 68

CAS No. 2436762-89-7

C₁₄H₁₃BrN₄O₂

M.W. 348.022

L-4481

Linagliptin

Linagliptin Impurity 69

CAS No. 188111-79-7

C₁₀H₂₀N₂O₂

M.W. 200.28

L-4482

Linagliptin

Linagliptin Impurity 70

C₁₆H₁₃BrN₆O₂

M.W. 401.22

L-4483

Linagliptin

Linagliptin Impurity 71

C₁₄H₁₈N₆O₂

M.W. 302.34

L-4484

Linagliptin

Linagliptin Impurity 72 Trifluoroacetate

C₂₅H₃₀N₈O₃. C₂HF₃O₂

M.W. 490.57 114.02

L-4485

Linagliptin

Linagliptin Impurity 73

C₂₅H₂₈N₈O₃

M.W. 488.552

L-4486

Linagliptin

Linagliptin Impurity 74

CAS No. 14785-95-6

C₆H₈N₄O₃

M.W. 184.155

L-4487

Linagliptin

Linagliptin Impurity 75

CAS No. 586408-08-4

C₁₀H₁₀N₄O₂

M.W. 218.216

L-4488

Linagliptin

Linagliptin Impurity 76

C₁₀H₁₁ClN₂O

M.W. 210.661

L-4489

Linagliptin

Linagliptin Impurity 77

C₁₀H₁₁ClN₂O

M.W. 210.661

L-4490

Linagliptin

Linagliptin Impurity 78

C₁₀H₁₁ClN₂O

M.W. 210.661

L-4491

Linagliptin

Linagliptin Impurity 79

C₁₆H₁₆N₂O

M.W. 252.317

L-4492

Linagliptin

Linagliptin Impurity 80 (2-Piperidinamine)

CAS No. 45505-62-2

C₅H₁₂N₂

M.W. 100.165

L-4493

Linagliptin

Linagliptin Impurity 81

C₂₀H₁₇BrN₆O₂

M.W. 453.300

L-4494

Linagliptin

Linagliptin Impurity 82

C₅₀H₄₀Br₂N₁₄O₄

M.W. 1060.772

L-4495

Linagliptin

Linagliptin Impurity 83

C₂₀H₁₈Br₂N₆O₂

M.W. 534.212

L-4496

Linagliptin

Linagliptin Impurity 84

C₃₀H₃₇N₇O₆

M.W. 591.669

L-4497

Linagliptin

Linagliptin Impurity 85

C₂₇H₃₀N₈O₂

M.W. 498.591

L-4498

Linagliptin

Linagliptin Impurity 86

C₂₂H₂₂N₆O₃

M.W. 418.457

L-4499

Linagliptin

Linagliptin Impurity 87

CAS No. 1673546-62-7

C₂₇H₂₇F₃N₈O₃

M.W. 568.56

L-44100

Linagliptin

Linagliptin Impurity 88

C₂₇H₃₂N₈O₂

M.W. 500.61

L-44101

Linagliptin

Linagliptin Impurity 89

C₂₆H₃₀N₈O₂

M.W. 486.58

L-44102

Linagliptin

Linagliptin Impurity 90 HCl

C₁₅H₂₀N₆O₂. HCl

M.W. 316.37 36.46

L-44103

Linagliptin

Linagliptin Impurity 91

C₂₄H₂₆N₈O₂

M.W. 458.53

L-44104

Linagliptin

Linagliptin Impurity 92

CAS No. 2428491-17-0

C₁₆H₁₃BrN₆O₂

M.W. 401.224

L-44105

Linagliptin

Linagliptin Impurity 93

C₂₆H₃₂N₈O₃

M.W. 504.60

L-44106

Linagliptin

Linagliptin Impurity 94

C₂₅H₂₇N₇O₃

M.W. 473.54

L-44107

Linagliptin

Linagliptin Impurity 95

C₂₇H₃₂N₈O₂

M.W. 500.61

L-44108

Linagliptin

Linagliptin Impurity 96

C₂₁H₂₄N₈O₂

M.W. 420.48

L-44109

Linagliptin

Linagliptin Glucoside (Mixture of Diastereomers)

C₃₁H₃₈N₈O₇

M.W. 634.69

L-44110

Linagliptin

Linagliptin Impurity 97 Trifluoroacetate (Mixture of Isomers)

C₃₃H₃₉F₃N₈O₉. C₂HF₃O₂

M.W. 634.70 114.02

L-44111

Linagliptin

Linagliptin Impurity 98

C₃₁H₃₈N₈O₇

M.W. 634.69

L-44112

Linagliptin

Linagliptin Impurity 99

C₃₁H₄₀N₁₀O₂

M.W. 584.73

L-44113

Linagliptin

N-Nitroso Linagliptin Impurity 91

C₂₄H₂₅N₉O₃

M.W. 487.52

L-44114

Linagliptin

Linagliptin Impurity 100

C₃₄H₃₄N₈O₄

M.W. 618.70

L-44115

Linagliptin

Linagliptin Impurity 101

CAS No. 1573118-33-8

C₃₄H₃₂N₈O₄

M.W. 616.68

L-44116

Linagliptin

Linagliptin Impurity 103 Trifluoroacetate

C₂₁H₂₄N₈O₂. C₂HF₃O₂

M.W. 420.48 114.02

L-44117

Linagliptin

N-Nitroso Linagliptin Impurity 103

C₂₁H₂₃N₉O₃

M.W. 449.48

L-44118

Linagliptin

N-Nitroso Linagliptin Impurity 90

C₁₅H₁₉N₇O₃

M.W. 345.36

L-44119

Linagliptin

N-Nitroso Linagliptin Impurity 43

C₃₀H₃₅N₉O₅

M.W. 601.67

L-44120

Linagliptin

Linagliptin Impurity 104

C₃₂H₃₂N₈O₂

M.W. 560.66

L-44121

Linagliptin

Linagliptin Impurity 105

C₃₂H₃₂N₈O₂

M.W. 560.66

L-44122

Linagliptin

Linagliptin Impurity 106

C₅₇H₆₀N₁₆O₄

M.W. 1033.22

L-44123

Linagliptin

Linagliptin Impurity 107

CAS No. 2137744-33-1

C₂₆H₂₈N₈O₃

M.W. 500.56

L-44124

Linagliptin

Linagliptin Impurity 108

C₃₁H₄₀N₁₀O₂ HCl

M.W. 584.73 36.46

L-44125

Linagliptin

Linagliptin Impurity 109

C₃₁H₄₀N₁₀O₂ HCl

M.W. 584.73 36.46

L-44126

Linagliptin

N-Nitroso Linagliptin Impurity 27

C₂₅H₂₇N₉O₃

M.W. 501.55

L-44127

Linagliptin

Linagliptin impurity 110

C₂₅H₂₆N₁₀O₄

M.W. 530.55

L-44128

Linagliptin

Linagliptin impurity 111

C₂₅H₂₇N₉O₃

M.W. 501.55

L-44129

Linagliptin

Linagliptin impurity 112

C₅₁H₅₅N₁₇O₅

M.W. 986.12

L-44130

Linagliptin

Linagliptin impurity 113

C₄₅H₄₃N₁₅O₅

M.W. 873.94

L-44131

Linagliptin

Linagliptin Impurity 114

CAS No. 1446263-39-3

C₂₅H₂₉BrN₈O₂

M.W. 553.47

L-44132

Linagliptin

Linagliptin Impurity 115

C₂₃H₂₆N₈O₂

M.W. 446.52

L-44133

Linagliptin

Linagliptin Impurity 116

C₂₅H₂₈N₈O₃

M.W. 488.55

L-44134

Linagliptin

N,N'-Dinitroso Linagliptin Impurity 17

C₅₁H₅₄N₁₈O₆

M.W. 1015.11

L-44135

Linagliptin

Linagliptin Impurity 117

C₂₅H₂₉N₇O₄

M.W. 491.55

L-44136

Linagliptin

Linagliptin Impurity 118

C₂₇H₃₄N₈O₃

M.W. 518.62

L-44137

Linagliptin

Linagliptin Impurity 119

CAS No. 6140-11-0

C₁₀H₁₀ClNO₂

M.W. 211.65

L-44138

Linagliptin

Linagliptin Impurity 120

C₂₆H₂₉N₇O₂

M.W. 471.57

L-44139

Linagliptin

Linagliptin Impurity 121

C₂₅H₃₀N₈O₂

M.W. 474.57